AFREZZA-INDUCED PULMONARY INFILTRATE

A Case of an Enigmatic Pulmonary Infiltrate

The differential diagnosis of a pulmonary mass in an immunosuppressed host with a history of cancer is broad and includes malignant, infectious and inflammatory etiologies. Mycobacterium avium complex (MAC) is a rare cause of opportunistic infection in susceptible individuals that can present as either localized or disseminated disease. On radiologic studies, the pulmonary disease can manifest ...

Afrezza (Insulin Human) Inhalation Powder

INTRODUCTION According to the National Diabetes Statistics Report, 29.1 million people have diabetes mellitus (DM) in the U.S., or approximately 9.3% of the population.1 DM imposes a fi nancial burden on both patients and the health care economy, with direct and indirect costs totaling $245 billion in 2012.1 All patients with type-1 DM (T1DM) require insulin therapy. Patients with type-2 DM (T2...

Extensive carbamazepine eruption with eosinophilia and pulmonary infiltrate.

NEW DRUG APPROVALS Inhaled Insulin Afrezza For Diabetes

NEW DRUG APPROVALS Inhaled Insulin Afrezza For Diabetes The FDA has approved a rapid-acting inhaled insulin to improve glycemic control in adults with diabetes mellitus. Insulin human inhalation powder (Afrezza, MannKind Corporation) is administered at the beginning of each meal. The product’s safety and effectiveness were evaluated in 3,017 participants—1,026 with type-1 diabetes and 1,991 wit...

Immune infiltrate in cancer

cancer research. While malignancy was (and is) generally considered as a cell-autonomous genetic and epigenetic disease, it turned out that cancer has also an immunological connotation [1]. Only if the immune system fails to eliminate the (pre-)neoplastic cells cancer can emerge and progress. During their lifetime, cancer cells are under the scrutiny of immune effectors. Only those malignant ce...